WYETH-AYERST LABORATORIES -- WALPB030 HYDROMORPHONE HYDROCHLORIDE INJECTION -- 6505-00F040236
=====================  Product Identification  =====================

Product ID:WALPB030 HYDROMORPHONE HYDROCHLORIDE INJECTION
MSDS Date:11/16/1992
FSC:6505
NIIN:00F040236
MSDS Number: BXLGC
=== Responsible Party ===
Company Name:WYETH-AYERST LABORATORIES
Box:8299
City:PHILADELPHIA
State:PA
ZIP:19101-5000
Country:US
Info Phone Num:610-902-5171/610-688-4400
Emergency Phone Num:610-902-5171/610-688-4400
CAGE:0HMG4
=== Contractor Identification ===
Company Name:WYETH-AYERST LABORATORIES
Box:City:PHILADELPHIA
State:PA
ZIP:19101-5000
Country:US
Phone:610-902-5171
CAGE:0HMG4

=============  Composition/Information on Ingredients  =============

Ingred Name:DIHYDROMORPHINONE HYDROCHLORIDE	    *95-1*
CAS:71-68-1
RTECS #:QD2625000
Fraction by Wt: 0.1-0.4%

Ingred Name:BENZYL ALCOHOL
CAS:100-51-6
RTECS #:DN3150000
Fraction by Wt: >1%

Ingred Name:WATER
CAS:7732-18-5
RTECS #:ZC0110000
Fraction by Wt: >1%

=====================  Hazards Identification  =====================

Routes of Entry: Inhalation:YES  Skin:NO  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:INHALATION: IF SUFFICIENT QUANTITIES
    ARE ABSORBED, SYSTEMIC POISONING MAY OCCUR. INGESTION: MAY CAUSE
    ANOREXIA, INSOMNIA, IMPAIRED MENTAL & PHYSICAL PERFORMANCE. MAY
    CAUSE THE CNS DEPRESSION. POISONIN G MAY ALSO AFFECT THE
    RESPIRATORY, CARDIOVASCULAR & GASTROINTESTINAL SYSTEMS. (SEE SUPP)
Explanation of Carcinogenicity:NONE
Effects of Overexposure:DRY MOUTH/SLURRED
    SPEECH/HEADACHE/NAUSEA/VOMITING/DIZZINESS/DROWSINESS/WEAKNESS/DEPRE
    SSED COUGH REFLEX/TREMORS/VISUAL
    DISTURBANCES/PRURITUS/SWEATING/SLIGHT DECREASE IN BODY TEMP/MOOD
    CHANGES/ANXIETY/A GITATION/EXCITEMENT/HALLUCINATIONS/INCREASED PAIN
    TOLERANCE/MUSCULAR RIGIDITY/STUPOR/SEDATION/UNCONSCIOUSNESS (SEE
    SUPP)
Medical Cond Aggravated by Exposure:PERSONS W/MYXEDEMA.

=======================  First Aid Measures  =======================

First Aid:INHALATION: MOVE TO FRESH AIR. IF NOT BREATHING, GIVE CPR.
    KEEP WARM/AT REST. TREAT SYMPTOMATICALLY/SUPPORTIVELY. SKIN: WASH
    W/SOAP/MILD DETERGENT & LARGE AMOUNTS OF WATER FOR	15-20 MINS.
    EYES: WASH	W/LARGE AMOUNTS OF WATER/NORMAL SALINE FOR  15-20 MINS.
    INGESTION: TREAT SYMPTOMATICALLY/SUPPORTIVELY. IF VOMITING, KEEP
    HEAD LOWER THAN HIPS TO AVOID ASPIRATION. OBTAIN MEDICAL ATTENTION
    IN ALL CASES

=====================  Fire Fighting Measures  =====================

Flash Point:>213F
Extinguishing Media:DRY CHEMICAL, CO2, WATER SPRAY/REGULAR FOAM. LARGER
    FIRES: WATER SPRAY, FOG/REGULAR FOAM
Fire Fighting Procedures:MOVE CONTAINER FROM FIRE SAFELY W/OUT RISK.
    DON'T SCATTER MATERIAL W/HIGH PRESSURE WATER STREAMS. DIKE FOR
    LATER DISPOSAL. AVOID BREATHING VAPORS. KEEP UPWIND.
Unusual Fire/Explosion Hazard:SLIGHT FIRE HAZARD WHEN EXPOSED TO
    HEAT/FLAME.

==================  Accidental Release Measures  ==================

Spill Release Procedures:SHUT OFF IGNITION SOURCES. STOP LEAK SAFELY
    W/OUT RISK. USE WATER SPRAY TO REDUCE VAPORS. SMALL: TAKE UP
    W/SAND/OTHER ABSORBENT & PLACE INTO CONTAINERS FOR LATER DISPOSAL.
    LARGE: DIKE FAR AHEAD. ISOLA TE AREA & DENY ENTRY. KEEP UNNECESSARY
    PEOPLE AWAY

======================	Handling and Storage  ======================

Handling and Storage Precautions:STORE AWAY FROM INCOMPATIBLE
    SUBSTANCES. AVOID CONTACT W/STRONG OXIDIZERS, EXCESSIVE HEAT,
    SPARKS/OPEN FLAME.
Other Precautions:AVOID PROLONGED/REPEATED CONTACT W/THIS SUBSTANCE.
    PREVENT EYE CONTACT.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:ANY CHEMICAL CARTRIDGE RESPIRATOR W/ORGANIC
    VAPOR CARTRIDGE W/A DUST & MIST FILTER. ANY SCBA W/A FULL FACEPIECE
    OPERATED IN A PRESSURE-DEMAND/OTHER POSITIVE PRESSURE MODE.
Ventilation:LOCAL EXHAUST/GENERAL DILUTION SYSTEM
Protective Gloves:RECOMMENDED
Eye Protection:SPLASH PROOF SAFETY GLASSES
Other Protective Equipment:NOT REQUIRED.
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
    REUSE.
Supplemental Safety and Health
PH: 4.4-4.6. HEALTH HAZ CONT'D: REPEATED/PROLONGED INGESTION MAY CAUSE
    PULMONARY FUNCTION, INCREASED BODY TEMP, MYOGLOBINURIA & RENAL
    FAILURE. SYMPTOMS CONT'D: COMA, REFLEXES & MUSCLE TWITCHING, CONVU
    LSIONS, IRREGULAR BREATHING, APNEA, CYANOSIS, FLUSHING OF THE
    SKIN/FACE, ARRHYTHMIAS, SHOCK, RASHES, CONSTIPATION.

==================  Physical/Chemical Properties  ==================

pH:(SUPP)
Appearance and Odor:CLEAR SOLUTION

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
ACIDS, BASES, OXIDIZERS
Stability Condition to Avoid:EXCESSIVE HEAT, SPARKS, OPEN FLAME & OTHER
    IGNITION SOURCES
Hazardous Decomposition Products:TOXIC/HAZARDOUS GASES

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE W/LOCAL, STATE &
    FEDERAL REGULATIONS.

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